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CPT Pathology and Laboratory Guidelines

PATHOLOGY & LABORATORY (80047 – 89398)

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  • The Pathology and Laboratory section of the CPT manual is formatted according to type of test performed—automated multichannel, panels, assays, and so forth.

 

  • Laboratories have built-in indicators that allow additional tests to be performed without a written order from the physician. These standards are set by the medical facility and imply that when a certain test is positive, it is assumed that the physician would want further information on the condition and specific additional tests performed.

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  • You will code only after the tests are performed, because an order for a laboratory test does not ensure that the test will be performed. This standard ensures that all laboratory tests performed are reported

 

  • Remember that what the physician ordered may not be all the laboratory work performed, depending on the facility’s policy concerning indicators.

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  •  The services in the Pathology and Laboratory section include the laboratory tests only. The collection of the specimen is reported separately from the analysis of the test.

 

  • Most Pathology and Laboratory subsections contain notes. Whenever notes are available, be sure to read them before assigning codes from the subsection because specific information pertinent to the codes is contained in these notes.

  • Remember that what the physician ordered may not be all the laboratory work performed, depending on the facility’s policy concerning indicators.

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  • The services in the Pathology and Laboratory section include the laboratory tests only. The collection of the specimen is reported separately from the analysis of the test.

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  • Most Pathology and Laboratory subsections contain notes. Whenever notes are available, be sure to read them before assigning codes from the subsection because specific information pertinent to the codes is contained in these notes.

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Organ or Disease-oriented panels

 

• The codes in the Organ or Disease-Oriented Panels subsection (80047- 80081) are grouped according to the usual laboratory work ordered by a physician for the diagnosis of or screening for various diseases or conditions.

 

• Groups of tests may be performed together using automated equipment, depending on the situation or disease.

 

• For example, during the first obstetric visit, a mother is commonly asked to have baseline laboratory tests performed to ensure that appropriate antepartum care is provided.

 

• To assign a panel code, each test listed in the panel description must be performed. Additional tests are reported separately. The development of panels saves the facility from having to report each test separately, and it is often more economical for the patient.

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• You cannot assign modifier -52 (reduced service) with a panel.

 

• For example, if all of the tests in the obstetric panel were done except the syphilis test, you could not report 80055 (Obstetrical Panel) with modifier -52. You would instead list each of the tests separately.

 

NOTE: Be careful when coding multiple panels on the same day for the same patient. Sometimes several panels include some of the same tests. For example, a hepatitis B surface antigen test is included in both the obstetric panel and the acute hepatitis panel. It would be inappropriate to report the same test twice.

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• The laboratory and pathology reports in the patient medical record will describe the method by which the test was performed. There are many different methods of performing the same test. For example, a urinalysis can be automated or nonautomated and can include or exclude microscopy. It is necessary to know these details if you are to assign the correct urinalysis code. If the details you need are not in the medical record, ask the laboratory staff or physician for further clarification. Drug Assay

 

• Laboratory Presumptive Drug Class Screening (80305-80307) is performed to identify the presence or absence of a drug. Testing that determines the presence or absence of a drug is qualitative (the drug is either present or not present in the specimen)

 

• The screening of drug classes is divided by method, including visual, instrument, and chemical. Codes 80305- 80307 report drug screening of any number of drug classes.

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Therapeutic Drug Assays

• Therapeutic drug assays (80150-80299) test for a specific drug and for the amount of that drug. Many types of drugs are listed in this subsection. If the drug is not listed, it is possible that quantitative analysis may be listed under the methodology (e.g., immunoassay, radioassay).

 

• Therapeutic drug assays are performed to help the physician monitor the level of medication in the patient’s system or to monitor the patient’s compliance. • The drugs are listed by their generic names, not their brand names. A Physician’s Desk Reference that lists pharmaceuticals by the generic and brand name will be helpful as you code drug testing and assays. • One location of Drug Testing codes in the index of the CPT manual is under the main term “Drug,” subtermed by the reason for the tests —analysis or confirmation. Therapeutic Drug Assay subsection codes can be found under the main term “Drug Assay” and subterms of the material examined, for example, amikacin, digoxin.

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Evocation/Suppression testing

 

• Evocative/Suppression (80400-80439) testing is performed to measure the effect of evocative or suppressive agents on chemical constituents. For example, 80400 is reported when a patient undergoes testing to determine whether adrenocorticotropic hormone (ACTH) is being produced in the body. The patient may have adrenal gland insufficiency.

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• To code the components of Evocative/Suppression Testing consider the following:

 

• If the physician supplied the agent, report the supply using 99070 from the Medicine section or a HCPCS code.

 

• If the physician administered the agent, report the infusion or injection with codes 96365-96379 from the Medicine section.

 

• If the test involved prolonged attendance by the physician, report the service with the appropriate E/M code. NOTE: Remember that the codes from the Pathology and Laboratory section are only for the tests performed and do not reflect the complete service provided to the patient.

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• A clinical pathologist, upon request from a primary care physician, will perform a consultation to render additional medical interpretation of test results.

 

• There are two codes under the subsection Consultations (80500, 80502). These consultations are based on whether the consultation was limited or comprehensive. A limited consultation is one that was done without the pathologist’s review of the medical record of the patient, and a comprehensive consultation is one in which the medical record was reviewed as a part of the consultative services. When either of these consultation codes is submitted to a third-party payer, the submission is accompanied by a written report.

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Consultation (Clinical Pathology)

 

• These are not the only consultation codes in the Pathology and Laboratory section of the CPT manual. There are also consultation codes toward the end of the section in the Surgical Pathology subsection (88321-88334) that report the services of a pathologist who reviews and gives an opinion or advice concerning pathology slides, specimens, material, or records that were prepared elsewhere or for pathology consultation during surgery.

 

• Pathology consultations during surgery are provided to examine tissue removed from a patient during a surgical procedure. If the pathologist did not use a microscope to examine the tissue, report 88329. If a microscope was used to examine the tissue, report 88331 or 88332, depending on the number of specimens that were examined.

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 • A specimen is a sample of tissue from a suspect area; a block is a frozen piece of a specimen; and a section is a slice of a frozen block. A pathologist prepares a specimen by cutting it into blocks and taking sections from the blocks.

 

• The number of sections taken depends on the judgment of the pathologist as to the number of areas of the specimen that need to be examined. The frozen section is placed (mounted) on a slide or held by other means that allow the pathologist to view the tissue under a microscope. • When one block is sectioned and examined, the service of examining that first section is reported using 88331. The second and subsequent sections of the same block are included in the reporting of 88331. If another block from another area (a second block) was sectioned, the first section would be reported using 88331, and subsequent sections from the second block using 88332. You cannot use 88332 without first reporting 88331. Code 88332 is marked as an add-on code (one that is used only with another code), its function is to report subsequent sections that were examined.

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Urinalysis, Molecular Pathology, and Chemistry

 

• Many types of tests are located under the Urinalysis, Molecular Pathology, and Chemistry subsections (81000- 84999).

 

• Urinalysis codes are for nonspecific tests performed on urine. Chemistry codes are for specific tests performed on material from any source (e.g., urine, blood, breath, feces, sputum)

 

• For example, a urinalysis using a dipstick (81000-81003) would report the presence and quantity of the following constituents: bilirubin, glucose, hemoglobin, ketones, leukocytes, nitrite, pH, protein, specific gravity, and urobilinogen. Any number of these constituents may be analyzed and reported using a code from the Urinalysis subsection (81000-81099)

 

• However, if the physician ordered an analysis of the urine specifically to determine the presence of urobilinogen (reduced bilirubin) and the exact amount of urobilinogen present (quantitative analysis), you would choose a code (84580) from the Chemistry subsection.

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• The main things to remember when coding from these two subsections are:

 

• Identify specific tests

• Determine if the test was automated (by machine) or nonautomated (manual)

• Number of tests performed

• Identify combination codes for similar types of tests

• Whether the results are qualitative or quantitative

• Method of testing

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• The Molecular Pathology codes are divided into Tier 1 and Tier 2 codes.

 

• Tier 1 codes (81161, 81200-81383) report services for molecular assays that are more commonly performed.

 

• For example, 81211 is an essay to determine the presence of a breast cancer gene—BRCA1 (breast cancer 1) and BRCA2 (breast cancer 2).

 

• There are many conditions in which a genetic predisposition can be predicted, such as cystic fibrosis and colon cancer.

 

• Tier 2 codes 81400-81479 involve less commonly performed analyses and are arranged by the required level of technical resources and the level of physician interpretation or other qualified health professional.

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Hematology and Coagulation

 

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• The Hematology and Coagulation subsection contains codes (85002- 85999) based on the various blood drawing methods and tests. The method used to perform the test is often what determines code assignment.

 

• A blood count is used to measure the kind and number of cells in the blood, such as red and white blood cells.

 

• It is a commonly used test to detect various abnormalities in the blood. Blood counts can be manual or automated, with many variations of the tests.

 

• For example, codes in the range 85004-85049 are blood count codes divided by method (manual or automated) and type of count, such as white blood count (WBC, 85004-85009) or a complete blood count (CBC, 85025, 85027).

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• To accurately code a blood count, the method and the type of the count must be documented.

 

• There are codes within the Hematology and Coagulation subsection for blood smear and bone marrow smear interpretations (85060, 85097)

 

• When a physician procures the bone marrow by means of aspiration, the service is reported with a code from the Surgery section (38220); but that is only part of the service. The other part of the service is the pathology analysis of the aspirated specimen. As the coder in a clinic setting, you may be reporting only the surgical services or only the pathology/laboratory services or a combination of both. When reporting the surgical services, always review the pathology report as a part of the code assignment, and when reporting the pathology services, always review the operative report.

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• There are many blood coagulation tests located in the Hematology and Coagulation subsection.

 

• The codes are divided based on the particular factor being tested. Great care must be taken to ensure that the correct coagulation factor has been reported based on the information in the medical record. Coagulation factor tests analyze the level of certain proteins in the blood that enable the blood to congeal properly. Low levels of a factor may result in excessive bleeding and high levels may lead to clot formation (thrombosis).

 

• For example, 85610 reports a test to assess the level of factor II (also known as a prothrombin). This test is often performed when a patient is on a blood thinning medication and the physician wants to determine if the factor is at the optimal level.

 

• Most of the tests in the Hematology and Coagulation subsection can be located in the index of the CPT manual under the name of the test, such as prothrombin time, coagulation time, or hemogram.

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Immunology

 

• Immunology codes (86000-86804) report identification of conditions of the immune system caused by the action of antibodies (e.g., hypersensitivity, allergic reactions, immunity, and alterations of body tissue).

 

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Transfusion Medicine

 

• The Transfusion Medicine subsection codes (86850-86999) report tests performed on blood or blood products. Tests include screening of blood for antibodies, Coombs testing, autologous blood collection and processing, blood typing, compatibility testing, and preparation of and treatments performed on blood and blood products.

 

• Transfusion of blood and blood components is reported with codes from a variety of locations. For example, to report the actual blood transfusion, assign 36430 from the Surgery section of the CPT manual. You must also report the substance being transfused, such as whole blood, HCPCS code P9010 per unit or red blood cells, P9021 per unit. The blood bank would provide and report the collection, processing, and storing of the autologous blood with 86890.

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Microbiology

 

• Microbiology codes (87003-87999) report the study of microorganisms and include bacteriology (study of bacteria), mycology (study of fungi), parasitology (study of parasites), and virology (study of viruses).

 

• Culture codes for the identification of organisms as well as the identification of sensitivities of the organism to antibiotics (called culture and sensitivity) are located in this subsection.

 

• Culture codes must be read carefully because some codes report screening only to detect the presence of an organism; some codes indicate the identification of specific organisms; and others indicate additional sensitivity testing to determine which antibiotic would be best for treatment of the specified bacteria. You report all tests performed on the basis of whether they are quantitative or qualitative and/or a sensitivity study.

 

Anatomic pathology

 

  • Anatomic Pathology codes (88000-88099) report examination of body fluids or tissues in postmortem (after death) examination. Postmortem examination involves the completion of gross, microscopic, and limited autopsies. Codes are divided according to the extent of the examination. This subsection also contains codes for forensic examination and coroner’s call.

 

  • For example, some codes report an examination without the central nervous system (88000, 88020), with the brain (88005, 88025), with the brain and the spinal cord (88007, 88027), etc. There are two codes for each extent because one is a gross examination, and one is a microscopic examination.

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Cytopathology and Cytogenic studies

 

• The Cytopathology subsection codes (88104-88199) report the laboratory work performed to determine whether cellular changes are present. For example, a very common cytopathology procedure is the Papanicolaou smear (Pap smear). Cytopathology may also be performed on fluids that have been aspirated from a site to identify cellular changes. Cytogenetic Studies (88230-88299) include tests performed for genetic and chromosomal studies. Surgical Pathology

 

• Surgical Pathology codes (88300-88399) describe the evaluation of specimens to determine the pathology of disease processes. When choosing the correct code for pathology, identify the source of the specimen and the reason for the surgical procedure.

 

• The Surgical Pathology subsection codes are divided into six levels (Levels I through VI) based on the specimen examined and the level of work required by the pathologist. Pathology testing is performed on all tissue removed from the body. The surgical pathology classification level is determined by the complexity of the pathologic examination.

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• Level I pathology code 88300 identifies specimens that normally do not need to be viewed under a microscope for pathologic diagnosis (e.g., a tooth)—those for which the probability of disease or malignancy is minimal.

 

• Level II pathology code 88302 deals with those tissues that are usually considered normal tissue and have been removed not because of the probability of the presence of disease or malignancy, but for some other reason (e.g., a fallopian tube for sterilization, foreskin of a newborn).

 

• Level III pathology code 88304 is assigned for specimens with a low probability of disease or malignancy. For example, a gallbladder may be neoplastic (benign or malignant), but when the gallbladder is removed for cholecystitis (inflammation of the gallbladder), it is usually inflamed from chronic disease and not because of cancerous changes.

 

• Level IV pathology code 88305 designates a higher probability of malignancy or decision making for disease pathology. For example, a uterus is removed because of a diagnosis of prolapse. There is a possibility that the uterus is malignant or that there are other causes of disease pathology.

 

• Level V pathology code 88307 classifies more complex pathology evaluations (e.g., examination of a uterus that was removed for reasons other than prolapse or neoplasm).

 

• Level VI pathology code 88309 includes examination of neoplastic tissue or very involved specimens, such as a total resection of a colon.

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• The remaining codes at the end of the subsection classify specialized procedures, utilization of stains, consultations performed, preparations used, and/or instrumentation needed to complete testing. The surgical pathology codes are located in the index under the main term “Pathology and Laboratory” and subterm “Surgical Pathology.”

 

NOTE: A specimen is defined as tissue submitted for examination. If two specimens of the same area are received and examined, each specimen is reported. For example, if two separately identified anus tags are received and each is examined, report 88304 × 2. If one anus tag is received and two different areas of the tag are examined, report 88304 only once.

 

Other Procedures

 

• Other Procedures includes miscellaneous testing on body fluids, the use of special instrumentation, and testing performed on oocytes and sperm.

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****END OF NOTES*****

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